Nikon ECLIPSE Ji

Digital Microscope

Smart Imaging System

Research Microscope Power in a Benchtop Assay Instrument

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Upgradable with confocal and super-resolution.

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Smart Imaging for cellular assays.

Key Features

Smart Experiments with Automated Assay

Effortless Results using AI

Data-Rich Microscopy

Smart Experiments with Automated Assays

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Simple Operation

Utilizing Nikon’s precision optical hardware, all of the advantages of high sensitivity and resolution from a research-level microscope are retained by an AI-driven, easy-to-operate benchtop laboratory instrument. ECLIPSE Ji also fits standard laboratory benchtops, has built-in vibration dampening hardware, and shields the sample from bright room light. There is no need for dedicated space or dark rooms to perform efficient imaging assays.

Assay types

Intensity Measurement:
Compares protein expression level changes in cells and cell nuclei in multiple wells.

Cell Counting (endpoint):
Counts the number of cell nuclei in a fixed sample and the area of the well occupied by cells.

Transfection Efficiency:
Investigates the percentage of cells expressing the target protein, and reports the expression efficiency.

Size & Morphological analysis:
Analyzes cellular morphology with measurements of the cell nucleus, cytoplasm, and the size of the cell region.

Cytotoxicity:
Measures the percentage of dead cells among all cells and evaluates cytotoxicity.

Apoptosis:
Measures the percentage of apoptotic cells among the population.

DNA damage (gamma H2AX):
Analyzes DNA damage foci within individual cell nuclei.

Nuclear Translocation:
Measures the nuclear translocation of NF-κB, indicating an extra-cellular stimulus.

Autophagy:
Measures the number of autophagosomes, their area, and their fluorescence intensity.

Effortless Results using AI

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Easy Cellular Imaging

ECLIPSE Ji’s Smart Experiment software interface uses newly developed artificial intelligence (AI), implemented to minimize errors and maximize data collection.

Single-Cell Imaging and Analysis with ease

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All in Automatic

AI based on Deep Learning defines acquisition settings and image analysis parameters, saving researchers valuable time at the microscope.

User Interface Designed for Data-Rich Microscopy

Images and corresponding analysis data for the plate, well, and each cell is contained in an interactive and linked interface. Users can navigate and quickly visualize trends and results.

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Multi-Role Digital Inverted Microscope

Outside of plate assays, ECLIPSE Ji can also serve as a digital research microscope, and can be integrated with a variety of peripheral hardware ranging from filter wheels through confocal systems such as "AX", or high-sensitivity cameras.

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*Photos and Videos courtesy of Nikon official website

Related Information

Intelligent Acquisition System

With Nikon microscope and software NIS-Elements, our high content imaging streamlines high-speed imaging and simple operations. Nikon software provides a dedicated interface for high content acquisition and analysis routines.

Without the need to adjust the focusing method, wavelengths, filters, and camera settings, it is easier to process alongside your research quickly and effortlessly. 

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Applications

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High Content Imaging

A study of living cells using microscopy to obtain a better understanding of biological function through the study of cellular dynamics.

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Fluorescence

Fluorescence itself is a form of luminescence that results from matter emitting light of a certain wavelength after absorbing electromagnetic radiation. Fluorescence Imaging help visualize biological processes taking place in a living organism.

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Neurobiology / Optogenetics

Is the study of the nervous system. The scope of neuroscience has broadened over time to include different approaches, such as optogenetics, a biological technique to control the activity of neurons or other cell types with light. This is achieved by the expression of light-sensitive ion channels, pumps, or enzymes specifically in the target cells.

Related Products

Microscope

Nikon Confocal Microscope System
AX / AX R
Nikon Super Resolution N-SIM
Nikon Super Resolution N-STORM
Spinning Disk Confocal

Camera

PCO. Fluoresence Lifetime Imaging Cameras
FLIM
PCO. High-Speed Cameras
Dimax
Nikon Scientific Color Cameras
Digital Sight 10
Nikon Scientific Monochrome Cameras
DS-Qi2

Software

Nikon NIS-Elements
High Content Analysis HC
Nikon NIS-Elements C
Nikon NIS-Elements AR
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