Tomocube HT Series

Holotomographic microscope

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New Era in Label-Free Live Cell Imaging

Holotomographic Microscopy

New era of microscopy Tomocube’s holotomography series utilize optical diffraction tomography (ODT), which enables users to quantitatively and noninvasively investigate biological cells and tissues. ODT reconstructs the 3D refractive index (RI) distributions of live cells and by doing so, provides structural and biochemical information about the cell including dry mass, morphology, and dynamics of the cellular membrane.

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White Blood Cells in 3D, Timelapse

A549 Cells in 3D

Osteoblast in 3D

Car-T Cells in 3D, Timelapse


Zero Stress to Cells

Label-free Imaging

High Resolution

Optical resolution below 200 nm (Max. 110 nm)

Fast Imaging

No sample preparation and Rapid 3D cell imaging

Quantitative Bioimaging

RI distribution, local cytoplasmic concentration, dry mass, calculated morphological parameters



2D/3D Overlay


3D Digital Color Coding

TomoStudio™ works in concert with our HT models, to visualized and analyze RI tomograms. With TomoStudio™, users can color code the image according to refractive index and identify various types of quantitative data.

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AI enhanced automatic single cell analysis & Quantification of subcellular organelles.

*Photos and videos courtesy of Tomocube official website


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